Genetic complementation in heterokaryons of human fibroblasts defective in cobalamin metabolism.
نویسندگان
چکیده
منابع مشابه
Genetic complementation in heterokaryons of human fibroblasts defective in cobalamin metabolism.
Inherited methylmalonicacidemia due to deficiency of methylmalonyl-CoA mutase (methylmalonyl-CoA CoA-carbonylmutase; EC 5.4.99.2) activity results from at least three classes of biochemically distinct defects affecting cobalamin (Cbl: vitamin B12) metabolism (cbl A, cbl B, and cbl C mutants) and a fourth class producing a defective mutase apoenzyme. We have obtained genetic evidence in support ...
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In vivo aging of human fibroblasts does not alter nuclear plasticity in heterokaryons.
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1975
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.72.8.3181